| Academic Decathlon | To assist members in preparing for scholarship opportunities & college scholars’ programs; encourage scholastic growth in students. |
| Advanced Placement Club | To promote AP classes and students and create an AP culture on our campus. |
| American Red Cross Society | To help individuals and families in need. |
| Ascension (Dance Company) | To give dedicated dancers who demonstrate extra effort and talent the opportunity to develop as a performer and choreographer. |
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To provide an opportunity for students to explore, enrich & facilitate through hands-on-learning. |
| Band | To support the band, have fun, fundraise, and entertain the community. |
| Be A Leader Club | To increase the number of students attending college by developing leadership skills, training and mentoring. |
| Bronies of Skyline | For those students that are fans of the TV Show "My Little Pony: Friendship is Magic" to watch and discuss it. |
| Cambridge Club | To promote Cambridge students and curriculum. Participate in service learning opportunites and community service. |
| Catering Club | To create opportunities for students to gain real world experience relating to the field of culinary arts. |
| Choir | Assist in the monetary needs of the choral program through fund raisers to support choral programs. |
| Christian Club | To allow like-minded Christians the opportunity to fellowship and to learn from each other. Also, the purpose is to help students follow Christ and reach out to those who are not yet Christians. |
| Club Entrepreneur | To reach out to individuals who seek becoming an entrepreneur. Also to form great thinkers and possibly create a business. |
| Conspiracy Club | To create a a peaceful environment to discuss conspiracy theories on a structured system and schedule. |
| Cooking Coyotes | Instructing and support aspiring young chefs while serving the immediate community. |
| Coyote Connection Leaders | Leadership organization that provides service to Skyline parents, students and community members during orientation, campus tours, etc. |
| Coyote TV | To provide opportunities for students to learn how to make movies and learn the use of video equipment and how to edit. |
| Dance | To give all dance students the opportunity to perform in a concert. |
| DECA | Helps students develop skills and competence for marketing careers, build self-esteem, experience leadership, practice community service. |
| Elements In Motion | To promote community service. |
| Engineering Club | To provide students with career choices, career opportunities, service learning opportunities and fun activities in the various fields of Engineering Sciences. |
| F.C.A. | To provide a club for christian students. Also to provide opportunities for any student to worship Jesus Christ if they so wish. |
| F.E.A. | To prepare students in a future teaching profession. Build personal development, a successful transition to college & professional development. |
| Fitness Club | To become physically fit and health by walking, etc. (and encouraging each other) support group. |
| HERO Club | Promote leadership opportunities, fundraising activities and service projects for Cooperative Education students. |
| Hip Hop Club | To provide a club to learn the style of hip hop and bring its form to the student body. |
| JROTC Coyote Club | To help motivate students to become better citizens. |
| Key Club | To provide a club whose sole purpose is to provide service to the community. |
| Latin Dance Club | Teach others how to dance Latin moves. Also to offer preforming opportunities as well. |
| National Honor Society | To create enthusiasm for scholarship, to stimulate a desire to render service, to promote leadership and to develop character. |
| Order of the Phoenix | To allow students to talk about the journey of Harry Potter. |
| Orchestra Council | To help the orchestra program to run in an efficient manner. |
| OSA - Outdoor Student Activity | Support AP Enviromental science, support student activites and promote stewardship. |
| Paw Pals | To enhance the lives of people with disabilities by providing opportunities for one-to-one friendships and integrated school activities. |
| Physics/Astronomy Club | To further explore physics and astronomy through various projects, experiments, trips and contests. |
| Robotics | To inspire young people to be science & technology leaders by engaging them in exciting mentor-based Robotic programs. |
| RPG - Role Playing games | Foster teamwork, creativity and social interaction through role playing games. |
| SC-09 Tutoring Club | To help students taking SC-09 be a more successful student. |
| Skybound Yearbook | To publish a yearbook as an historical record of the year while teaching students desktop publishing and journalism skills. |
| Skylights | A journal with artists and authors to release their artistic creativity. |
| Sophisticated Coyotes | "Work-based" club to give students in the Transition from School-to-Work Program (TSW) Experience with work related activites. |
| Sports Medicine | Assist head athletic trainer with providing sports medicine coverage of Skyline athletic teams. |
| Stage Crew | To give students an opportunity to work on stage, help with rentals, plays, dance concerts or any other event in the auditorium. |
| Student Council | Promote school spirit, community service, and student leadership activities. |
| Theatre Club | Enhance cultural awareness of the arts through participation of stage acting, stage production, & audience participation for theatrical events. |
| We the People | Constitution club with government competition. |
Athletic Team Clubs – Skyline has a club for each athletic team, which includes:
Boys: Baseball, Basketball, Cross Country, Football, Golf, Soccer, Swim/Dive, Tennis, Track, Volleyball, Wrestling
Girls:Badminton, Basketball, Cross Country, Golf, Soccer, Softball, Spiritline, Swim/Dive, Tennis, Track, Volleyball